I-45 SOUTH (Coming from Dallas, The Woodlands, Conroe, Bush Intercontinental Airport) Take I-45 South> to I-10 East > to US-59 South > exit Downtown Destinations > right on Capitol > left on Avenida de las Americas.

I-45 NORTH (Coming from Galveston, NASA, Clear Lake, Houston Hobby Airport) Take I-45 North > exit Downtown Destinations (Pease Street Exit #45) > right on Chartres > left on Capitol > left on Avenida de las Americas.

US-59 SOUTH (Coming from Kingwood, Humble, Bush Intercontinental Airport) Take US-59 South > exit Downtown Destinations > left on Franklin Street > right on Hamilton > right on Capitol > left on Avenida de las Americas.

US-59 NORTH (Coming from the Galleria, Missouri City, First Colony, Sugarland) Take US-59 North > exit Downtown Destinations (Polk Street) > left on Polk > turn right on Avenida de las Americas.

I-10 WEST (Coming from Baytown, Channelview, New Orleans) Take I-10 West > To US 59 South > exit Hamilton/Downtown Destinations > right on Capitol > left on Jackson > left on Rusk > right on Avenida de las Americas.

I-10 EAST (Coming from Katy, San Antonio) Take I-10 East > exit Downtown Destinations (Smith Street Exit) > left on McKinney > right on Avenida de las Americas.

SH-288 NORTH (Coming from Pearland, South Loop, Reliant Park) Take SH-288 North > to US-59 North > exit Downtown Destinations (Polk Street) > left on Polk > right on Avenida de las Americas.

SH-290 EAST (Coming from Austin, Copperfield) Take SH-290 East > to Loop 610 South > to I-10 East > to US-59 South > exit Downtown Destinations > turn right on Capitol > left on Avenida de las Americas.